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Pages: 1 2 3 4 5 6 7 8 9 Showing 1 - 20 of 177 for anti smith. (0.004 seconds)


... smith antibody and anti ds dna for about 8 months. I've been on Plaquenil for almost three years. ... (0 replies)
Anti-smith
Jul 29, 2002
... Does anyone know HOW specific the anti-smith antibody is to lupus??? Is there anyone who tested positive for the anti-smith? and what did your doctor say??? (2 replies)
... Nope, not at all. They arent a sign of impending doom. Its sort of like ANA, most people have an ANA titer, which is why the positive cutoff is between 1:40 and 1:160 (childrens titer cutoff is lower 1:20 I think), but most dont and never will have an autoimmune. Now it is possible, since you have SSB and symptoms that over time other antibodies may become positive. Thats... (6 replies)

... Thanks for your reply! Yes- my Anti-dsDNA is only a 1, out of a range 0-9. The anti-smith are 0.3 out of a range of 0.0-0.9. And my ssa is 0.2 and ssb is 1.7 out of a range of 0.0-0.9. So really, the ssb is the only high one. I was just trying to understand if the others, although not positive, are a bad sign. (6 replies)
... Thanks for the response. Actually, I think the anti-DNA is considered negative but the anti-Smith is my concern. I've read a number of times that one can be pretty much diagnosed based only on a positive anti-Smith result. I've also read, however, that I need to meet 4/11 criteria/characteristics to be officially diagnosed. I don't know what to think or expect and have to... (5 replies)
... If they're not flagged, then they're probably *not* positive. Its possible to have numbers of greater than 0, but less than the cutoff, in healthy people. You could post your results with reference ranges, if you want. dsDNA is not often seen in healthy people, but it depends on the actual dsDNA assay used, most are very specific but lower dsDNA is seen in other... (6 replies)
Anti La Antibody
Apr 26, 2004
... Can someone tell me more about the Anti LA antibody? ... (4 replies)
... Are these anti-bodies found in people that do not have lupus? I have both, but the numbers are very low, so they're not flagged. I've seen in a number of places online that anti-dsDNA and anti-sm are pretty exclusive to Lupus. Not sure what to think! (6 replies)
... te getting a diagnosis and starting treatment so you can begin to feel better. There is no point in waiting 3 months. I agree lupus is a strong possibility since anti ds DNA is positive. How high was that, and how high was your ANA? ... (8 replies)
... Hdisco, I think Vee covered a lot of good info. You are not crazy! Only a few things I can add-if you can get actual copies of your test results, and care to post them here, it would be helpful. Please be sure to put reference (normal) ranges with your levels, as that can change depending on type of test done and lab. It is important to know how high the dsDNA antibodies were... (2 replies)
... Hi Everyone - Here's a little background. I started feeling bad in college, lost a lot of weight for no reason, etc. I never went to the doctor mostly because I was scared of what they might find (foolish - I know). Now fast forward about 10 years and I start feeling really bad. This is all flared up after taking Zithromax for a sinus infection. I went to my Dr.... (1 replies)
Anti-smith results
Jul 14, 2006
... Crafty, I was too stupid to get copies of test results over the 8+ years of bloodwork & skin biopsies leading up to Dx = the SCLE "subset". My anti-Ro did go down after the few months of Plaquenil. I think the anti-Sm and anti-Ro are probably titer tests? Are yours expressed as ratios? If they are titers, one "dilution" can therefore be the dividing line between... (1 replies)
Anti-smith results
Jul 13, 2006
... Has anyone ever had their anti-sm and/or anti-ro test results be positive one time and negative another? (1 replies)
... Thanks teachergirl64 for the info. I am praying that when i go see the rheumy he will shed some light into all this. God bless. (15 replies)
... I found what the different ANA patterns meant and here's what it said about yours. The Homogenous pattern is very specific to lupus and requires dsDNA, ssDNA and anti-Smith for further evaluation The rheum you see will repeat the ANA panel and run the additional tests. Good luck with the waiting. It is hard. (15 replies)
... I saw some posts looking for info on Tumid LE. From what I gather, it is a variant of subacute cutaneous Lupus Erythematosus (SCLE). Here is some information. * * * Tumid Lupus Erythematosus: criteria for classification with immunohistochemical analysis. Alexiades-Armenakas MR, Baldassano M, Bince B, Werth V, Bystryn JC, Kamino H, Soter NA, Franks AG Jr. New... (0 replies)
Is this SLE?
Jul 11, 2017
... My case was similar to yours. My anti-smith was very high. I don't have rash, but do have inflammation. The doctor told me, you can have lupus without anti-smith being positive, but it is rare for a person to have positive anti-smith and not have lupus. I think you need to see a new Rheumy. CCC (3 replies)
Equivocal ds dna
Mar 31, 2015
... Actually, This picture is not so bleak. Your dsDNA is high enough to warrant retesting. It tends to go up prior to and during a flare of symptoms. If your WBC tends to hover below 4000, that is significant also, along with your symptoms. So, The ds DNA should be repeated during your next flare up of symptoms, IMO, and anti-Smith, anti-RNP, anti-cardiolipin or anti-phospholipid... (6 replies)
... I'm sorry you're struggling with so many symptoms. I reacted to your post the same way Ladybug did. I'd want to see the "specialty blood labs", the ones containing tests for ANA subtypes. There should be many, including anti-ds-DNA, anti-Smith, anti-Ro, anti-La, anti-RNP, antiphospholipid, anticardiolipin, rheumatoid factor, ETC. While only two, anti-ds-DNA and anti-Smith, are... (32 replies)
... I know this thread is a bit old, but a negative ANA test, negative Anti-Smith and Anti-RNP doesn't rule out Lupus or Sjögrens or other autoimmune diseases. The criteria was changed. A diagnosis does not depend solely on tests but a little bit of both tests (like C3, C4, anemia, nephrotic syndrome, etc) and symptoms. If you google seronegative Lupus or seronegative Sjögren's,... (34 replies)




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