It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....

Lyme Disease Message Board

Lyme Disease Board Index

I've been sick for 5 years and recently went to a "Lyme Disease Specialist".

He works out of a building complex next to a fast food restaurant and staffs only three people.

He did the Western Blot on me and also the Urine test for Lyme.
Urine test was negative, Western Blot was positive.. by his standards.

I have only had maybe 4 tickbites in my life, never had a bullseye rash, and they were all when I was a child, nearly 15 years ago.

I have some of the symptoms of Lyme Disease, but well... who doesn't, the list fits just about everyone and every condition on earth.

By CDC standards the western blot was negative, but I understand there is some controversy over that.

Since receiving the test results, I have tried 5 different antibiotics (oral) as prescribed by the doctor.
They have not helped at all.

The doctor has around 5 more lined up and then, if those don't help, he wants me to start over at the beginning and try Intravenous.

Now I am no fan of having a catheter(sp) in my arm for the next few months, but that is beside the point really.

I am trying to figure out if I should continue trying all of these things which will probably take up another year of my life if it is probably to no avail and cost godly amounts of money, when I could be visiting another doctor and getting diagnosed with another problem if I have it.

Every doctor I have talked to around where I live says that the Western Blot was negative and I do not have lyme disease, except for this doctor, but as I said before, I understand there is some controversy about it, and he IS a designated "Lyme Specialist", at least by his own standards.

Here is my western blot results.

If you have knowledge about it, could you please lend me some advice as to if you think this is a credible and POSITIVE western blot test, and if you think it is worth my trouble to continue with this whole new course of antibiotics when the current ones have done no good... not to mention a few "test' antibiotics that are not FDA approved (/shivers at the thought).

(My doctors standards for testing:)
The IgM WB is considered positive for the presence of AB to B. Burgdorferi if two of the starrded bands are present: 23-25, 31, 34, 39, 41 kDa.
The IgM WB is considered equivocal if one of the starred bands is present.
(CDC standards for testing:)
An IgM WB is positive if two of these bands are present: 23-25, 39, 41 kDa. New York State Deparment of Health considers WB positive that conform to the ASTPHLD/CDC criteria.

**41 kDa +/-

Only one reactive band on the test.

NEGATIVE by Doctor and CDC standards.


(My doctors standards for testing:)
The IgG WB is considered positive if two of the starred bands are present: 23-25, 31, 34, 39, 41, 93 kDa.
The IgG WB is considered equivocal if one of these bands are present: 23-25, 31, 34, 39, 93 kDa.
41 kDa, by itself, is negative.
(CDC standards for testing:)
An IgG WB is positive if five of these bands are present: 18, 23-25, 28, 30, 39, 41, 45, 58, 66, 93kDa. New York State Department of Health considers WB positive that conform to the ASTPHLD/CDC criteria.

**34 kDa +/-
**41 kDa ++
**58 kDa +
66 kDa +/-

NEGATIVE by CDC standards, Positive by Doctor's standards.


What i'm wondering is this - Is it possible that I can have those bands show up and still NOT have or had Lyme Disease in the past?
I understand the test looks for antibodies to certain proteins of bacteria.
Could my body be producing antibodies to those bacteria in response to some other illness other than Lyme disease?
What % chance do you think there still would be that I have Lyme Disease after looking at my test results and the fact that I will have tried 10 different antibiotics to cure it?

If anyone knows where I could find this information or offer some of your own advice if you are knowledgable on this subject, please do.

Thanks for your time.
Hi Johnpr. Are you having symptoms? First of all, are you sure your doctor is knowledgeable about Lyme? Why would he prescribe antibiotics that are not approved by the FDA? This would make me very suspicious. Where do you live?

Although a bullseye rash is a definite sign of Lyme Disease, only about 50% of people who have Lyme ever get a rash. Often, people are bitten by ticks without them knowing it because they are very small and inject a numbing agent so you cannot feel them on you. Even if the last time you were bitten was 15 years ago, it is still possible you have Lyme. It can lie dormant for a long period of time.

No Lyme test is completely reliable. Even the CDC (who is behind the times regarding Lyme Disease) states that a negative test does not rule out Lyme. There is an over reliance on tests when it is supposed to be a clinical diagnosis.

How long have you stayed on each antibiotic? It can take quite some time to tell if an antibiotic is working. Have you been tested for the co-infections that ticks can transmit--Babesiosis, Ehrlicihiosis HME & HGE, and Bartonella? Many people who have Lyme are co-infected and it will affect treatment choice and progress. Many doctors believe the co-infections need to be treated before Lyme treatment is effective.

The IgM Western Blot tests for a more recent infection and the IgG tests for a longer-standing infection. It is rare to have the number of bands required by the CDC for the test to be positive. Some bands are specific for Lyme. Here are the meanings of the bands you have:

~~Band 34 is specific for Bb (Lyme bacteria)
~~Band 41 is usually the first to show after a Bb infection
~~Band 58 is unknown but may be a heat-shock Bb protein
~~Band 66 is cross-reactive for all Borrelia, common in all bacteria

Do you know which lab did your test? Some labs are better than others.

I am interested in your responses regarding the number of antibiotics you have taken and for how long, and whether or not you have been tested for the co-infections. From what I understand of band results, I think you have Lyme. I would recommend getting another opinion, especially if this doctor is considering giving you unapproved medications.

All times are GMT -7. The time now is 11:11 PM.

© 2020 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!