It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Lyme Disease Message Board


Lyme Disease Board Index


Hi Diane, welcome to the board!

I am sorry you are feeling so bad. I know it is frustrating trying to find an answer.

No Lyme test is completely reliable. Regarding the Western Blot, the CDC requires several bands to be present for it to be positive; however, many people who have Lyme do not have this many bands show. Lyme doctors often focus on which bands are positive, some are specific for Lyme. Below is the breakdown of the bands:

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

It is my understanding that the IgM tests for a more recent infection and the IgG a longer standing one. Band 41 is often the first to show, and yours is positive. Bands 34 and 39 are Lyme specific and yours are IND. I think this is significant.

It is very important to see a knowledgeable doctor. Many doctors do not understand Lyme and treat with outdated protocols. Besides Lyme, ticks can transmit several co-infections including Babesiosis, Ehrlichiosis (HME & HGE), Bartonella, and Mycoplasma. Many people who have Lyme are co-infected, and it may affect treatment choice and progress. It is important to be tested for these by a Lyme reputable lab such as IgeneX in Palo Alto, CA. If you would a doctor recommendation, let us know.

It is also important to learn as much as possible. I recommend reading "Everything You Need To Know About Lyme Disease (2nd edition)" by Karen Vanderhoof-Forschner, and Dr. Burrascano's treatment guidelines. He is one of the top Lyme doctors in the country, and many doctors follow his protocols.

Do not give up, you will find out what is wrong. Hang in there okay?





All times are GMT -7. The time now is 08:57 AM.





© 2020 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!