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Lyme Disease Message Board


Lyme Disease Board Index


Hi FlaGal. Why does the Lyme doctor want you to see an oncologist, because of your WBC?

Is he planning on treating the Babesiosis? Many Lyme doctors believe the co-infections need to be treated first for Lyme treatment to be effective.

Regarding the Western Blot, the IgM tests for a more recent infection and the IgG a longer standing one. Below is the breakdown of the Western Blot bands:

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

Although the CDC requires a large number of bands to be present for it to be positive, many people who have Lyme do not have this many bands. Lyme doctors often look at which bands are present--some are specific for Lyme.

Band 41 is often the first to show. Bands 23-25, 31, 39, and 83 are Lyme specific bands. Yours are either positive or IND, which is significant.

Hang in there okay?





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