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[QUOTE=ktp812;2945290]I was wondering if anyone can interpret my IgeneX results also. I keep having serious doubts if I actually have LD. I also have Adrenal Insufficiency. My test was done back in November.
IGG
31 IND
39 IND
41 +++

IGM
23-25 IND
39 IND
I was considered negative from both CDC and Igenex. I have been on antibiotics since November and definately herxed very badly. I don't know why but I just am not sure. I don't think the doctor would have me on all these abx's if I didn't have Lyme. Any ideas?
Kim[/QUOTE]

That is considered a negative western blot. However, if you re-tested 4-6 weeks after being on antibiotics, you are likely to see those IND's turn to + or even ++'s. The antibacterial effect stirs up the bacteria making it more likely to get a positive result after first starting. Herxheimers only occur w/ Lyme and Syphillis. Did your doctor say you herxed?? You most likely do have lyme then.

My results from Stonybrook Lab, Igenex and Medical Diagnostic were about the same---and I got positive PCR, Microscopy and co-infections...so I dont doubt my diagnosis.

My bands were:

18 +++
23 +
30 +
31 ++
34 +++
39 IND
41 +++
58 IND
66 ++
83/93 ++
Hi lizzie. Below is the breakdown of the Western Blot bands:

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

No test for Lyme is completely reliable. Many people who have Lyme test negative. On thOn the Western Blot, the CDC requires a large number of bands to show for it to be considered positive, yet many people who have Lyme do not have this many bands show. Lyme doctors often focus on which bands show, some are specific for Lyme.

Band 41 is often the first to show. Bands 23-25, 30, 34 and 39 are Lyme specific bands. These bands on your test are either + or IND. I think your results are significant. Were you tested for all the co-infections?

What meds are you taking?
Hi Kim.

Hi lizzie. Below is the breakdown of the Western Blot bands:

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

No test for Lyme is completely reliable. Many people who have Lyme test negative. On thOn the Western Blot, the CDC requires a large number of bands to show for it to be considered positive, yet many people who have Lyme do not have this many bands show. Lyme doctors often focus on which bands show, some are specific for Lyme.

Band 41 is often the first to show and yours is positive. Bands 23-25, 31, and 39 are Lyme specific bands and yours are IND. It is good you are being treated.

Which antibiotics are you taking? Were you tested for all the co-infections?





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