It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Lyme Disease Message Board


Lyme Disease Board Index


Hi Helene. Which lab did the Western Blot?

Remember that no Lyme test is completely reliable, and results can vary by lab. On the Western Blot, the CDC requires several bands to be present for the test to be positive; however, many people who have Lyme do not have this many bands. Lyme doctors often look at which bands are positive--some are specific for Lyme disease.

Below is the breakdown of the Western Blot:

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

Band 41 is often the first to show and band 39 is a Lyme specific band, and hers are positive. And she has symptoms. I recommend that you have her tested at IgeneX Lab in Palo Alto. They use more sensitive testing and list more bands on the Western Blot.

I am still hoping she may get in sooner with Dr. Jones. Hang in there okay?





All times are GMT -7. The time now is 06:49 PM.





© 2020 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!