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Lyme Disease Message Board

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Re: Glutathione
Jun 19, 2007

I recently came across some research by Dr. Paul Cheney, MD, PhD. (one of the foremost CFIDS researchers) regarding the role glutathione plays in inhibiting the growth and replication of intracellular pathogens.

Glutathione is a potent anti-viral and anti-microbial agent. Anthony Falci, the top HIV researcher at the NIH, has shown that HIV growth can be completely stopped by raising glutathione levels in-vitro in cell cultures. If glutathione levels can be raised, the replication of almost any pathogen inside the cells can be stopped. Obviously, this raises the question of its role in combatting tick-borne diseases, some of which (Borrelia burgdorferi, babesia microti) can be intracellular.

While the presence of glutathione is a microbe inhibitor, a deficency of glutathione can actually STIMULATES THE GROWTH OF PATHOGENS AND AUGMENTS VIRAL REPLICATION!

What I found interesting is that it was found that glutathione deficiency is overwhelmingly common in chronic fatigue patients. Does anyone know if there is any research regarding glutathione levels in Lyme patients?

The challenge has been finding a way to raise the levels of glutathione inside the cells themselves, where it is needed in order to be effective. Supplementation, injections, etc. did not significantly raise the levels in the cells. The most effective means found was the use of undenatured whey protein. This seems like a benign supplement to other treatments, one of those things that at worst won't do anything but can't do any harm. On the other hand anything that helps is always a plus.

Sorry if I've rambled, I'm having some brain fog issues today, just wanted to pass along this info.[/QUOTE]

Hi I've read the same research; it's really pretty fascinating. Have you tried using N-Acetyl Cysteine? It's been proven to boost Glutathione levels (I think it's actually a precursor), and is readily available at most health food stores. I've been using it for a while and it does seem to help. Interestingly, the Wheldon-Stratton protocol for Multiple Sclerosis/Chlamydia, uses it as a regular treatment option.
Curcumin works pretty well for brain fog.

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