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Multiple Sclerosis Message Board


Multiple Sclerosis Board Index


Hi,
I'm sorry this is so long! I've been being tested for MS for the past 6 months or so. My neurologist (an MS specialist) suspected MS when I went in for back pain and weird sensations and extreme debilitating eye pain in one eye, fingers twitching and numbness, muscles in arm and leg twitching, face on one side had lessened sensation, pain in my rib cage, malaise, electric shock in back of head at neck, and toes numb. In the past six months I've had episodes of drop foot, ataxic walk, cognitive impairment, electric shock/stabbing that starts in eyebrow and goes to the side of my cheek by my nose, lips going numb and bottom lip will start contracting, weakness in arms, burning on the top of my foot, and extreme pain on the bottoms of my feet, vibration in my abdomen and legs, eye twitching, and some visual disturbances... (the list could go on and on lol). Most things for the moment are at bay, but right now the most annoying thing as we speak I keep getting an electrical shock in my hand and my fingers are not cooperating as well as on the side of my nose (has been happening for 4 days)

I've had 2 rounds of MRI's w/wo contrast on my brain, neck, thoracic, and lumbar...only some patchy signal alteration within the cervical cord, non-specific signal alteration adjacent to the occipital horn of the right ventricle, and mild prominence of lymphatic tissues in the wildeyers ring, and a cyst on maxillary sinus. EMG/NCS study was normal except showed carpal tunnel in both wrists.

Dr. says it isn't MS but wanted to do further testing of my CSF because of the high nucleated cells. So he tested the ACE levels. The nurse recently called and said that everything is looking normal. But from my research an elevated CSF ACE level of 7 isn't normal, and could point to sarcoidosis. I had never actually heard of sarcoidosis or neurosarcoidosis until a couple of days ago when researching some of my LP results. Neurosarcoidosis is a mimic of MS and the other way around. My question is, how are these numbers normal? I haven't been able to talk to the Dr. yet, so I am wondering if anyone could give their advice on my results. Definitely not MS?? Neurosarcoidosis?? Thanks SO SO much!


CSF / Serum multiple sclerosis panel
Final
See *1
Results Expected Units
Oligoclonal bands, CSF 0 0 bands
Oligoclonal bands, serum 0 0 bands
Interpretation 0 See *2<4 bands
CSF IgG index 0.50 <=0.85 index
IgG, CSF 2.6 <=8.1 mg/dl
Albumin, CSF 28.1 [B]High[/B] <=27.0 mg/dl
Albumin/globulin ratio 0.09 <=0.21 ratio
Synthesis rate, CSF 0.50 <=12 mg/24 hr
IgG, serum 748 [B]Low[/B] 767-1590 mg/dl
Albumin, serum 090 3200-4800 mg/dl
IgG/albumin ratio 0.18 <=0.40 ratio

CSF cell count
Final
Result Expected Units
Color Colorless
Appearance Hazy
RBCs 787 [B]High[/B] 0 - 0 cells/mcl
Nucleated cells 18 [B]High[/B] 0 - 5 cells/mcl

CSF cell morphologic exam
Final
Result Expected Units
Neutrophils 25 [B]High[/B] 0 - 7 %
Lymphocytes 67 28 - 96 %
Monocytes 8 [B]Low[/B] 16 - 56 %


CSF protein
Final
Result Expected Units
Protein 43 12 - 60 mg/dl


CSF glucose
Final
Result Expected Units
Glucose 65 40 - 70 mg/dl


CSF angiotensin-converting enzyme (ACE)
Final
See *1
Result Expected Units
Angiotensin-converting enzyme 7 See *2 Units/L





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