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Muscular Dystrophy Board Index
Pages: 1Showing 1 - 16 of 16 for myo 029 myostatin. (0.003 seconds)

... Jin Lee is a researcher at Johns Hopkins studying myostatin and discusses some of his recent findings. ... (0 replies)
... Hello everyone, Has anyone heard any updates (or have first hand information) on the clinical trials Wyeth performed last year for MYO-029 (myostatin blocker)? I was hoping that they would have mentioned something about the results in their second quarter financial results yesterday, but they didn't. If I remember correctly they had stated that these results would have... (4 replies)
... Internet Image search on "Belgian Blue Cattle" and also "Myostatin Mighty Mice" These pictures will show you what happens if an animal is born WITHOUT myostatin. Myostatin is a substance in your body that keeps your muscles from growing huge and out of control. ... (42 replies)

... cannot move properly and if they do tendons tear like paper. One thing I havent read about but I have been thinking about lately is the result of introducing the myostatin drug and its affect on muscles that are still relatively strong compared to the muscles that have been weakening from the disease. ... (42 replies)
News on MYO-029
Mar 21, 2008
... it issued "Studies Shed More Light on Myostatin Blocking". ... (1 replies)
... by itself is not going to block myostatin production. ... (42 replies)
... I was wonderig if anyone has read anything about ACVR2B? It is a myostatin inhibitor that seems to work about 3 times as good as MYO-029. In 2005 Wyeth was doing clinical trials with mice, and found this out, while at the same time, they were doing human trials of the MYO-029. I wonder if that discovery is what is delaying the announcement on the MYO-029 results? You can... (9 replies)
... Hello everyone! I was just doing more research on the myostatin blockers (it's taking forever to get the results!) Wyeth is still analyzing results of clinical trials on their MYO-029 Myostatin Blocker, a potential way for those of us with MD to "grow new muscle tissue". Another company, Acceleron Pharma, is also fast-tracking research along the same lines - their blocker is... (15 replies)
... P.S has anyone tried the Myostatin blockers available to body builders? ... (15 replies)
... Allan1970. That is bad news though shouldnt be of too much surprise. Research has shown that simply inhibiting myostatin is not enough. ... (42 replies)
... Just been looking at folstaxan and again would love to hear from anyone who has tried it, may try it myself, what is there to loose! so has MYO-029 been unsuccessfull? (15 replies)
... the myo 029 haven't been promising so acceleron will be taking over the trials again this year (15 replies)
... Hi Arobbo - welcome to the Board! That's interesting that you were a part of the MYO-029 trial. Do you mind if I ask - what type of MD do you have, and give a little more detail if you would, on the positive results? It is encouraging to talk to one who's actually been through the process. I contacted Acceleron, as I'm interested in being involved in their clinical trials.... (15 replies)
... Mark Thank you for your response. She has LGMD2B. Both my aunt and uncle are carriers. They were checked. After speaking w/ my aunt I understand that she is doing physical therapy occassionally but doesn't want to commit. She's young and wants her life. Understandable in a way. She also is on vitamins and creatine. She told me they didn't do anything anyway. She... (5 replies)
... I believe the Wyeth trial is finished, and did not show any clear improvement. But there are many ways in which myostatin activity can theoretically be inhibited, so there will be a lot more work on this in the future. ... (4 replies)
... However I still remain hopeful. For those interested in the idea of Myostatin Inhibitors, look up articles or images of "Mighty Mice" or "Muscular German Baby" or Belgian Blue Cattle". ... (9 replies)

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