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Myositis Message Board

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Myositis can be part of autoimmune disorders such as lupus, mixed connective tissue disease, dermatomyositis, polymyositis and others. I would be sure your blood work has included a recent sedimentation rate, CRP, ANA, CPK, Rheumatoid factor, and thyroid studies, as well as urinalysis, liver and kidney function tests. Hyper(excess thyroid)thyroidism and hypo(insufficient)thyroidism can both cause muscle aches, pains, weakness and fatigue, as well as hyperactive active reflexes (hyperthyroid). There is a new lupus test out that is more sensitive than the standard, and I would ask for that. It is called AVISE-SLE (blood test).
A biopsy of your skin spots might help and the Dr. should ask for immunofluorescence studies with that to look for immune complexes deposited in the skin layers. Dermatomyositis usually causes extremely high CPK and aldolase levels, so that is unlikely but not impossible. Given your age and description with minimally elevated aldolase, lupus would be my first priority to rule out. Pursuing a diagnosis is important because then you can get on treatment and feel better!

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