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Cancer: Cervical & Ovarian Message Board

Cancer: Cervical & Ovarian Board Index

Michele - sorry to hear you are having abnormal cells show up on your pap again. How long has it been since your LEEP? Sometimes the pap will show abnormal but it's just the cervix doing its healing thing. I hope that's what it is!

Level 3 is also termed as: CIN 3 (Cervical interepithelial neoplasia), severe dysplasia, severe dyskariosis, and high grade squamous interepithelial lesion (HGSIL). I have no idea why they can't decide on one particular term - it is so confusing!

Basically, level three means that more cell layers are involved in the lesion. For example, if you have level one, only the top surface cells of the cervix are affected. Level two, the cells affected are a little deeper. Level three means the cells are just about involved in all the layers of the cervix. The next level is called carcinoma in situ (CIS), meaning the cells are involved in ALL layers of the cervix, but have not broken through the basement membrane. (I'm not sure how deep - less than a centimeter for sure). These are all considered PRE-CANCEROUS cell changes. Once the cells break through the basement membrane then you are looking at cancer.

did your doctor get clear margins when he did your LEEP (meaning, all the bad cells were removed, along with a bunch of healthy cells)? Did he tell you what the LEEP pathology said your lesion was? Sometimes the LEEP can come back showing different than the original biopsy. You might want to consider getting copies of your reports just to keep in your own file.

I hope this helps you a little bit, and that your next biopsy comes back showing no cell changes.



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