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Cancer: Cervical & Ovarian Message Board

Cancer: Cervical & Ovarian Board Index

Hi there. I also had AIS (considered stage 0 or pre-cancer) about 10 yrs ago. The difference between AIS and CIS is that with AIS abnormal cells originate from glandular cells, while with CIS they original from squamous cells. AIS is much more rare and aggressive. I don't know a whole lot more about it, but here's what I've been through. I had a cold knife cone biopsy (from what I understand they usually do this for AIS instead of LEEP) with clear margins, but now I have abnormal glandular cells again and am scheduled for a hysterectomy. I don't know how common it is for this to happen. I thought that since I had clear margins, it was gone, but apparently not. What i have now is not AIS, just abnormal cells, diagnosed by endocervical curettage. But i'm scared there might be something there they haven't seen yet. They didn't do any biopsies to see if it had spread last time. I guess because the margins were clear? I guess I wait to see what they find when the hysterectomy is done. It will be a laparoscope assisted vaginal hyst (LAVH) and they will leave my ovaries. Hope this is helpful regarding "what comes next" and hope you don't get this far! The cold knife cone wasn't bad at all, if that's any reassurance. I didn't have any other treatment than that. And then just monitoring frequently.
Good luck! There's lots of info on here on AIS if you dig around.

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