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Cancer: Prostate Message Board


Cancer: Prostate Board Index


Re: Max PSA Level
Aug 13, 2009
[QUOTE=iflyim777;4057480]Thank you again Jim for all of the insightful information!!! ...

[COLOR="darkgreen"]You're welcome. That's what the board is for, and we're glad to help! :)[/COLOR]

It is interesting that you mentioned a prostate or urinary tract infection because I have been experiencing some of these symptoms for several years now. If I do have a UTI, how much could this elevate this PSA number? If you could cast some light on this it would help me connect some dots.
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[COLOR="darkgreen"]I've heard that UTIs can raise PSA all by themselves to around 50, but I don't know how common that is. I heard of one case where the PSA rose to around 200 before the offending bacterium was found; the patient's PSA then dropped back to normal.

One thing you can do is to check out www.pubmed.gov, a site we can use on this board because it is sponsored by the Government (our taxpayer dollars doing priceless work via the NIH's National Library of Medicine). I just did a search and got 35 hits using the search string " urinary tract infection AND prostate specific antigen NOT prostate cancer " (without the quotes). Here's the citation for one, hit #8 as of this evening (will stay there until another relevant study is published that fits the search) which happens to have a link to the free article in PubMed:

Acute bacterial prostatitis: heterogeneity in diagnostic criteria and management. Retrospective multicentric analysis of 371 patients diagnosed with acute prostatitis.
Etienne M, Chavanet P, Sibert L, Michel F, Levesque H, Lorcerie B, Doucet J, Pfitzenmeyer P, Caron F.
BMC Infect Dis. 2008 Jan 30;8:12.

If you go to the paper and search for PSA, as I did, you find that the average (median) value of PSA in their fairly good sized study (hundreds of patients) was 17, with a range from 0 to 415. Unfortunately, they did not show a graph of PSA values.

Hit #29 is a smaller, older study of 31 men with this citation:
Prostate specific antigen in urinary tract infection.
Bell CR, Natale S, McInerney PD, Hammonds JC.
Br J Gen Pract. 1998 Feb;48(427):1005-6.

It doesn't have an abstract, but PubMed offers a free link to this brief paper also. They reported the average PSA in their group was 24, with a range from 5.4 to 100. They noted that the PSAs returned to normal or close to normal fairly quickly when the infections were resolved.

Those looked like the most helpful papers to me.

Take care,

Jim :wave:
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