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Cancer: Prostate Message Board

Cancer: Prostate Board Index

The rule of thumb used by many Dr's for assessing the possibility of prostate cancer based on percent free PSA is if the percent FPSA is between 10 and 25% some Dr's will recommend closer monitoring or possibly a biopsy. When the percent FPSA drops below 10 prostate cancer is usually suspected and a biopsy recommended. The bound or regular PSA becomes suspicious when it increases more than .75 ng/ml in a year
from the baseline level . When the PSA suddenly spikes, thats more indicative of an infection or prostatitis which is treated with anti-biotics and it should then subside. The regular PSA can also be elevated for up to 48 hours after an ejaculation or a vigorous DRE.
However when the PSA begins a steady rise and the percent FPSA is under 10, a biopsy is usually a good idea. The PSA velocity or rate of increase is a strong factor in reaching a tentative diagnosis and decision to do a biopsy.
Hope this adds a little clarity to a confusing scenario. Your urologist should be informing you of these parameters rather than simply administering anti-biotics.
Good Luck.

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