It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Restless Leg Syndrome Message Board


Restless Leg Syndrome Board Index


Hmmm, so you're not taking any other medications...ie...statins, antacids, antihistamines, beta blockers? Any medical conditions besides RLS? Even obesity/overeating has been implicated with the onset and/or severity of RLS.

Well, knowledge is power. So I'll pass along what I know and maybe you can figure out a way to improve your RLS enough to get more sleep. People with RLS have shoddy dopamine receptors and sub-normal levels of iron in the brain...which may actually cause the shoddy receptors. On the bright side, our brains have plenty of dopamine, maybe even more than the average bear ;). Those receptors are portholes that allow dopamine to travel down our spines (aka the central nervous system) and relax our legs and arms. Alas, we with RLS have just a trickle of that dopamine travelling along our spines because our receptors are so defective. And that drip may be enough. So for years and years and years we have no idea we have RLS, then one day we start statins, or get pregnant or develop rheumatoid arthritis and poof - all out RLS. Certain drugs and certain conditions hamper the release of dopamine. The vast majority of the world can take statins, get pregnant or have arthritis and will never feel so much as a twinge of RLS. But those of us who have so little dopamine kicking around our central nervous system can't afford any reduction. Even injuries to our spine can trigger RLS because that trickle of dopamine can't push past the site of the injury.

Science experiments have shown that the dopamine receptors (and specifically the D2 receptors) of lab rats increased dramatically when they were "under-fed." So consistently under-eating might be worth a shot. I, and others have found that 1/2 to one teaspoon of cream of tartar (which is pure potassium) gets rid of RLS for the night. One teaspoon exceeds the recommended daily allowance. Others swear by a teaspoon of mustard in water before bed. Some swear by niacin and magnesium but I found these to make my RLS worse. When I get an attack I run for iron and specifically iron bisglycinate. I have to take the pill (25 mg) on an empty stomach during an attack. It gets rid of the RLS for the night. It is not a cure. I am a woman but have the red blood count of a healthy male and the iron stores of Hercules. Yet my brain just can't call up any iron from my healthy stores. But while that iron is circulating in my bloodstream my brain can suck it up and temporarily my shoddy receptors are shored up.

There you have it. Anything that shores up our receptors such as under-eating or iron will help. Anything that causes a "pop" or "release" of dopamine such as potassium in large quantities or the quinine found in tonic water or the turmeric found in mustard will help...albeit temporarily.

Good luck and keep us posted.
[QUOTE=Blacktea;5365224]Hmmm, so you're not taking any other medications...ie...statins, antacids, antihistamines, beta blockers? Any medical conditions besides RLS? Even obesity/overeating has been implicated with the onset and/or severity of RLS.

Well, knowledge is power. So I'll pass along what I know and maybe you can figure out a way to improve your RLS enough to get more sleep. People with RLS have shoddy dopamine receptors and sub-normal levels of iron in the brain...which may actually cause the shoddy receptors. On the bright side, our brains have plenty of dopamine, maybe even more than the average bear ;). Those receptors are portholes that allow dopamine to travel down our spines (aka the central nervous system) and relax our legs and arms. Alas, we with RLS have just a trickle of that dopamine travelling along our spines because our receptors are so defective. And that drip may be enough. So for years and years and years we have no idea we have RLS, then one day we start statins, or get pregnant or develop rheumatoid arthritis and poof - all out RLS. Certain drugs and certain conditions hamper the release of dopamine. The vast majority of the world can take statins, get pregnant or have arthritis and will never feel so much as a twinge of RLS. But those of us who have so little dopamine kicking around our central nervous system can't afford any reduction. Even injuries to our spine can trigger RLS because that trickle of dopamine can't push past the site of the injury.

Science experiments have shown that the dopamine receptors (and specifically the D2 receptors) of lab rats increased dramatically when they were "under-fed." So consistently under-eating might be worth a shot. I, and others have found that 1/2 to one teaspoon of cream of tartar (which is pure potassium) gets rid of RLS for the night. One teaspoon exceeds the recommended daily allowance. Others swear by a teaspoon of mustard in water before bed. Some swear by niacin and magnesium but I found these to make my RLS worse. When I get an attack I run for iron and specifically iron bisglycinate. I have to take the pill (25 mg) on an empty stomach during an attack. It gets rid of the RLS for the night. It is not a cure. I am a woman but have the red blood count of a healthy male and the iron stores of Hercules. Yet my brain just can't call up any iron from my healthy stores. But while that iron is circulating in my bloodstream my brain can suck it up and temporarily my shoddy receptors are shored up.

There you have it. Anything that shores up our receptors such as under-eating or iron will help. Anything that causes a "pop" or "release" of dopamine such as potassium in large quantities or the quinine found in tonic water or the turmeric found in mustard will help...albeit temporarily.

Good luck and keep us posted.[/QUOTE]
@Blacktea- I'm an extreme neewbie here but a long time sufferer (45 yrs). Reading your explanation of RLS was informative and much more understandable than any other I've read. Thank you for that. I find it interesting that you mention dopamine 'release' being triggered by iron, quinine, turmeric and potassium. Perhaps for me that is an issue as I am allergic to quinine & iron supplements. Don't have a history with turmeric or potassium so I will try those cautiously.
Sometimes I wonder if I have something else rather than RLS because no one has my symptoms of spasmodic legs. They spasm/jerk, contract and contort. I don't HAVE to move them... they move on their own! :) Anyone else affected this way? Now it is starting in my upper body. I think it's rebound from too much Ropinolol or because of increase in Cymbalta. Any thoughts?





All times are GMT -7. The time now is 03:06 AM.





© 2020 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!